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South Carolina

Clinician license renewal in South Carolina

Renewal cycles, fees, CE requirements, and compact membership for nurse practitioners, physician assistants, and physicians in South Carolina. Sourced from state boards and the official compact registries; we surface the citation next to every claim and never invent a rule we can’t verify.

Last reviewed 05/08/2026.

Compact membership

Nurse Licensure Compact (NLC)

Full member

Source: nursecompact.com, as of 05/05/2026

Interstate Medical Licensure Compact (IMLC)

Not a member

Source: imlcc.com, as of 05/05/2026

APRN / nurse practitioner license

Renewal cycle
Biennial. APRN, RN, and LPN licenses all renew every 2 years under SC Nurse Practice Act § 40-33-40.
llr.sc.gov, as of 05/08/2026
Renewal fee
$145 APRN biennial renewal (with prescriptive authority) + $75 RN biennial renewal (as of 2026-05-08; SC LLR Fee Schedule). $220 total per biennium for prescribing APRN+RN. APRNs without prescriptive authority pay $105 biennial. Initial APRN application is $30 (SC RN already on file) or $140 by endorsement. Application for Prescriptive Authority is a separate $20 fee.
llr.sc.gov, as of 05/08/2026
Continuing education
South Carolina APRN biennial renewal requires documented evidence of at least ONE of the following during the preceding two years: (1) 30 contact hours from a Board-recognized continuing education provider, (2) maintenance of certification or re-certification by a national certifying body recognized by the Board, (3) completion of an academic program of study in nursing or a related field recognized by the Board, OR (4) verification of competency as evidenced by employer certification on a Board-approved form.
llr.sc.gov, as of 05/08/2026
Online renewal available
Confirm with South Carolina Board of Nursing (LLR)

Track this credential automatically with Larch’s License tracking.

Physician assistant license

Renewal cycle
Biennial. SC PA licenses are renewed every 2 years per LLR.
llr.sc.gov, as of 05/08/2026
Renewal fee
$45 biennial PA license renewal fee per the SC Board of Medical Examiners fee schedule (as of 2026-05-08). Confirm at the time of renewal with LLR.
llr.sc.gov, as of 05/08/2026
Continuing education
50 hours of Category 1 CME biennially, of which at least 20 hours must relate to the PA's practice area, per SC Board of Medical Examiners rules. PAs additionally maintain current NCCPA certification.
llr.sc.gov, as of 05/08/2026
Online renewal available
Confirm with South Carolina Board of Medical Examiners (LLR)

Track this credential automatically with Larch’s License tracking.

MD / DO license

Renewal cycle
Confirm with South Carolina Board of Medical Examiners (LLR)
Renewal fee
Confirm with South Carolina Board of Medical Examiners (LLR)
Continuing education
Confirm with South Carolina Board of Medical Examiners (LLR)
Online renewal available
Confirm with South Carolina Board of Medical Examiners (LLR)

We’re still verifying South Carolina Board of Medical Examiners (LLR)’s MD/DO- specific renewal details. The most accurate source is the board itself — visit South Carolina Board of Medical Examiners (LLR).

Track this credential automatically with Larch’s License tracking.

State controlled-substance registration

Some states layer a state-level controlled-substance registration (CSR or CDS) on top of the federal DEA; others rely on the DEA alone. Where South Carolinarequires one, it carries its own number, fee, and renewal clock — independent of the DEA cycle.

Required in this state
Confirm with South Carolina controlled-substances regulator

We’re still verifying South Carolina’s state CSR rules. Confirm with the South Carolinacontrolled-substances regulator (often the Board of Pharmacy or a Department of Health office) before assuming you do or don’t need a state CSR alongside your DEA.

Track DEA + state CSR together with Larch’s DEA + CSR tracker.

Federal DEA registration

DEA registration is federal, not state-issued. DEA practitioner registrations renew on a three-year cycle and are tied to a specific practice address — multi-site clinicians typically hold one DEA per practice location, each with its own number and clock. The first renewal on or after June 27, 2023 also required a one-time MATE Act 8-hour training attestation; once attested, the credit carries forward.

See Larch’s DEA tracking page for details on the federal cycle, multi-site rules, and the MATE Act attestation requirements.

Common questions about South Carolina renewals

Is South Carolina a Nurse Licensure Compact (NLC) state?
Yes — South Carolina is a full NLC member. Nurses who hold an active multistate license issued by another compact state may practice in South Carolina without applying separately, and South Carolina residents may apply for a multistate license through the South Carolina Board of Nursing if they meet the NCSBN's Uniform Licensure Requirements. Note that nurses changing their primary state of residence to or from a compact state generally must apply in the new home state within 60 days. Source: NCSBN compact map.
Does the Interstate Medical Licensure Compact (IMLC) work for physicians in South Carolina?
South Carolina is not currently a participating IMLC member. Physicians who want to practice in South Carolina must apply directly through the South Carolina Board of Medicine; they cannot use the IMLC's expedited pathway. Source: IMLCC.
Does the federal DEA renewal cycle differ in South Carolina?
No. DEA practitioner registrations are federal and renew on a three-year cycle regardless of state. Registrations are tied to a specific practice address — not to the holder personally — so multi-site clinicians typically hold one DEA per practice location. South Carolina's state-level controlled-substance registration, if it requires one, is separate from the federal DEA.
How does Larch keep South Carolina's rules current?
A drift-detection job re-fetches each cited source on a weekly cadence and flags pages where the source content has changed since our last review. Where we don't have a verified detail, we surface "Confirm with [Board]" with a link to the issuing board — never a guess.

Track every SC credential on one calendar.

Larch keeps a clean clock on every license, DEA, state CSR, board cert, and CE hour. Smart renewal alerts on the schedule you set. Encrypted document vault. License tracker is $5/month or $49/year — bundle with Collaboration + CE for $119/year.

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Sources for South Carolina

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