Is Mississippi a Nurse Licensure Compact (NLC) state?

Yes — Mississippi is a full NLC member. Nurses who hold an active multistate license issued by another compact state may practice in Mississippi without applying separately, and Mississippi residents may apply for a multistate license through the Mississippi Board of Nursing if they meet the NCSBN's Uniform Licensure Requirements. Note that nurses changing their primary state of residence to or from a compact state generally must apply in the new home state within 60 days. Source: NCSBN compact map.

Does the Interstate Medical Licensure Compact (IMLC) work for physicians in Mississippi?

Yes — Mississippi participates in the IMLC. Eligible physicians can use the compact's expedited pathway to obtain medical licenses in additional member states. Whether Mississippi serves as a physician's State of Principal License or only as a license-issuing state varies; check the IMLCC for current specifics. Source: IMLCC.

Does the federal DEA renewal cycle differ in Mississippi?

No. DEA practitioner registrations are federal and renew on a three-year cycle regardless of state. Registrations are tied to a specific practice address — not to the holder personally — so multi-site clinicians typically hold one DEA per practice location. Mississippi's state-level controlled-substance registration, if it requires one, is separate from the federal DEA.

How does Larch keep Mississippi's rules current?

A drift-detection job re-fetches each cited source on a weekly cadence and flags pages where the source content has changed since our last review. Where we don't have a verified detail, we surface "Confirm with [Board]" with a link to the issuing board — never a guess.

Mississippi

Clinician license renewal in Mississippi

Renewal cycles, fees, CE requirements, and compact membership for nurse practitioners, physician assistants, and physicians in Mississippi. Sourced from state boards and the official compact registries; we surface the citation next to every claim and never invent a rule we can’t verify.

Last reviewed 05/08/2026.

Compact membership

Nurse Licensure Compact (NLC)

Full member

Source: nursecompact.com, as of 05/05/2026

Interstate Medical Licensure Compact (IMLC)

Member

Source: imlcc.com, as of 05/05/2026

APRN / nurse practitioner license

Renewal cycle: Biennial. APRN renewal happens September through December of even-numbered years; the underlying CE cycle runs from January 1 of the odd year through December 31 of the even year.; msbn.ms.gov, as of 05/08/2026
Renewal fee: $100 APRN biennial renewal (Mississippi Board of Nursing). APRNs holding Controlled Substance Prescriptive Authority pay an additional $100 CSPA fee at each DEA renewal (every 3 years). Practice Site and Collaborative Physician fees are $25 each. The underlying RN biennial renewal is a separate fee not anchored on this APRN page.; msbn.ms.gov, as of 05/08/2026
Continuing education: Mississippi APRNs must complete a minimum of 5 contact hours of CE directly related to controlled substances per State Certification Period — required for ALL APRNs (CNPs, CNMs, CRNAs) regardless of whether they hold CSPA/DEA. Renewal cycle is January 1 of odd year through December 31 of even year. CE certificates are uploaded into CE Broker. APRNs must also maintain current national APRN certification (lapse requires immediate practice halt under Miss. Admin. Code Part 2840, Rule 1.2 B(5)).; msbn.ms.gov, as of 05/08/2026
Online renewal available: Confirm with Mississippi Board of Nursing

Track this credential automatically with Larch’s License tracking.

Physician assistant license

Renewal cycle: Annual license renewal with biennial CME compliance. PAs renew yearly; CME compliance is certified during renewal in even-numbered years.; msbml.ms.gov, as of 05/08/2026
Renewal fee: $150 annual PA license renewal fee per the MSBML License Fee Schedule (as of 2026-05-08).; msbml.ms.gov, as of 05/08/2026
Continuing education: 100 hours of continuing medical education every 2 years per MSBML rules, of which at least 50 hours must be Category 1. PAs authorized to prescribe controlled substances additionally complete at least 5 hours of CME every 2 years related to controlled-substance prescribing.; msbml.ms.gov, as of 05/08/2026
Online renewal available: Confirm with Mississippi State Board of Medical Licensure

Track this credential automatically with Larch’s License tracking.

MD / DO license

Renewal cycle: Confirm with Mississippi State Board of Medical Licensure
Renewal fee: Confirm with Mississippi State Board of Medical Licensure
Continuing education: Confirm with Mississippi State Board of Medical Licensure
Online renewal available: Confirm with Mississippi State Board of Medical Licensure

We’re still verifying Mississippi State Board of Medical Licensure’s MD/DO- specific renewal details. The most accurate source is the board itself — visit Mississippi State Board of Medical Licensure.

Track this credential automatically with Larch’s License tracking.

State controlled-substance registration

Some states layer a state-level controlled-substance registration (CSR or CDS) on top of the federal DEA; others rely on the DEA alone. Where Mississippirequires one, it carries its own number, fee, and renewal clock — independent of the DEA cycle.

Required in this state: Confirm with Mississippi controlled-substances regulator

We’re still verifying Mississippi’s state CSR rules. Confirm with the Mississippicontrolled-substances regulator (often the Board of Pharmacy or a Department of Health office) before assuming you do or don’t need a state CSR alongside your DEA.

Track DEA + state CSR together with Larch’s DEA + CSR tracker.

Federal DEA registration

DEA registration is federal, not state-issued. DEA practitioner registrations renew on a three-year cycle and are tied to a specific practice address — multi-site clinicians typically hold one DEA per practice location, each with its own number and clock. The first renewal on or after June 27, 2023 also required a one-time MATE Act 8-hour training attestation; once attested, the credit carries forward.

See Larch’s DEA tracking page for details on the federal cycle, multi-site rules, and the MATE Act attestation requirements.

Common questions about Mississippi renewals

Is Mississippi a Nurse Licensure Compact (NLC) state?: Yes — Mississippi is a full NLC member. Nurses who hold an active multistate license issued by another compact state may practice in Mississippi without applying separately, and Mississippi residents may apply for a multistate license through the Mississippi Board of Nursing if they meet the NCSBN's Uniform Licensure Requirements. Note that nurses changing their primary state of residence to or from a compact state generally must apply in the new home state within 60 days. Source: NCSBN compact map.
Does the Interstate Medical Licensure Compact (IMLC) work for physicians in Mississippi?: Yes — Mississippi participates in the IMLC. Eligible physicians can use the compact's expedited pathway to obtain medical licenses in additional member states. Whether Mississippi serves as a physician's State of Principal License or only as a license-issuing state varies; check the IMLCC for current specifics. Source: IMLCC.
Does the federal DEA renewal cycle differ in Mississippi?: No. DEA practitioner registrations are federal and renew on a three-year cycle regardless of state. Registrations are tied to a specific practice address — not to the holder personally — so multi-site clinicians typically hold one DEA per practice location. Mississippi's state-level controlled-substance registration, if it requires one, is separate from the federal DEA.
How does Larch keep Mississippi's rules current?: A drift-detection job re-fetches each cited source on a weekly cadence and flags pages where the source content has changed since our last review. Where we don't have a verified detail, we surface "Confirm with [Board]" with a link to the issuing board — never a guess.

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Larch keeps a clean clock on every license, DEA, state CSR, board cert, and CE hour. Smart renewal alerts on the schedule you set. Encrypted document vault. License tracker is $5/month or $49/year — bundle with Collaboration + CE for $119/year.

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Sources for Mississippi

msbn.ms.gov · retrieved 05/08/2026
msbml.ms.gov · retrieved 05/08/2026
msbml.ms.gov · retrieved 05/08/2026
NCSBN Nurse Licensure Compact Map (PDF) · retrieved 05/05/2026
Interstate Medical Licensure Compact Commission (IMLCC) · retrieved 05/05/2026

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